Press release
VESTAKEEP for Implants
September 22, 2021

Evonik and Samaplast expand the performance spectrum of plastic implants

Evonik will present the VESTAKEEP® Fusion biomaterial during the EUROSPINE trade show in Vienna, Austria (October 6-8, 2021) at the Booth 42.

  • Osteoconductive PEEK biomaterial for injection molding
  • Spinal cage prototype demonstrates design versatility
  • Product introduction at the EUROSPINE fair in Vienna (October 6-8) at booth 42.

Darmstadt, Germany. The specialty chemicals company Evonik and the Swiss plastics specialist Samaplast are combining their expertise in the development of an osteoconductive PEEK biomaterial for injection molding. As part of the collaboration, both partners are demonstrating and documenting the outstanding processing properties of the new osteoconductive high-performance polymer VESTAKEEP® Fusion using the first prototypes of spinal implants.

Biphasic calcium phosphate accelerates healing

Until now, it has been virtually impossible to manufacture implants from polymer compounds with bioactive particles by injection molding, because a thin polymer layer usually forms on the surface that overlays the particles, preventing the implant from growing in. But with VESTAKEEP® Fusion, the functional BCP additives (biphasic calcium phosphate) are also available on the surface of injection-molded components. This is ensured by the specially configured microparticles and their homogeneous distribution.

"Implant manufacturers were missing a PEEK material that fuse with bone cells and thus accelerates healing, for example after spinal surgery," says Marc Knebel, Head of the Medical Systems Market Segment at Evonik. "We are closing this gap in the market with VESTAKEEP® Fusion and offering an alternative to titanium, stainless steel or cobalt-chromium implants right away."

Osteoconductive PEEK biomaterial for injection molding

VESTAKEEP® Fusion was developed with a goal to process in different manufacturing technologies and is initially offered as granules and semi-finished products. It can be milled, compression molded, extruded-and even injection molded. For the latter, Evonik has optimized the compound in close cooperation with Samaplast AG.

"We tested VESTAKEEP® Fusion on injection molding machines in the clean room and found that it was very easy to process," confirms Samaplast CEO Stefan Okle. "Thanks to the excellent exchange with Evonik, we were able to produce a prototype within ten days." Previously, tool development alone had taken eight to ten weeks. With rapid prototyping, this process can be shortened considerably.

Cage prototype demonstrates the design diversity

Evonik and Samaplast are demonstrating what is possible with the first prototypes of intervertebral implants, known as cages or spacers, which are used to fill the disc space in the spine following its removal due to disc degeneration. "We have produced a cage that contains all the details, such as serrations, threads, and apertures, that are relevant for spinal implants," explains Okle.

Thanks to the design freedom in injection molding of VESTAKEEP® Fusion, specific cage variants can be produced - tailored to the anatomical conditions and different surgical techniques such as PLIF, TLIF and ALIF. The cage models show the design diversity in the interlocks and in the cavities for ossification. In addition, the design facilitates instrument guidance during surgery and also enables minimally invasive, patient-friendly surgical techniques.

Over 30 percent higher cell proliferation


With VESTAKEEP® Fusion, Evonik is introducing a new product line of next-generation PEEK-based implant materials. The osteoconductive properties of the new PEEK material were achieved by using a special functional additive - biphasic calcium phosphate - and allow bone cells to adhere to implants more quickly, thus positively influencing fusion, so called osteointegration, at the boundary between the bone and the implant. This, in turn, will accelerate bone fusion and convalescence.

In vitro studies document over 30 percent increased cell attachment and cell proliferation. In preclinical tests, histological examination reveals a dense network of newly formed osteoblasts at the bone-implant interface. Bone histomorphometry shows an approximately twofold increase in bone apposition. And pull-out tests demonstrate a more than twofold increase in implant fixation.

Evonik's polymer experts are also developing a 3D-printable VESTAKEEP® Fusion filament that could be processed in additive manufacturing using fused filament fabrication (FFF) technology.

Evonik will present the VESTAKEEP® Fusion biomaterial during the EUROSPINE trade show in Vienna, Austria (October 6-8, 2021) at the Booth 42.

About Evonik

Evonik is one of the world leaders in specialty chemicals. The company is active in more than 100 countries around the world and generated sales of €12.2 billion and an operating profit (adjusted EBITDA) of €1.91 billion in 2020. Evonik goes far beyond chemistry to create innovative, profitable and sustainable solutions for customers. About 33,000 employees work together for a common purpose: We want to improve life today and tomorrow.

About Smart Materials

The Smart Materials division includes businesses with innovative materials that enable resource-saving solutions and replace conventional materials. They are the smart answer to the major challenges of our time: environment, energy efficiency, urbanization, mobility and health. The Smart Materials division generated sales of €3.24 billion in 2020 with about 7,900 employees.


In so far as forecasts or expectations are expressed in this press release or where our statements concern the future, these forecasts, expectations or statements may involve known or unknown risks and uncertainties. Actual results or developments may vary, depending on changes in the operating environment. Neither Evonik Industries AG nor its group companies assume an obligation to update the forecasts, expectations or statements contained in this release.